What question did this study set out to answer?

To explore the spread of extended-spectrum β-lactamase-producing Enterobacterales in community living spaces and assess the influence of housing density.

April 21, 2026Open Access

Spread of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) in the community living spaces of patients identified as ESBL-E carriers: impact of the housing density in an African context

Key Points

To explore the spread of extended-spectrum β-lactamase-producing Enterobacterales in community living spaces and assess the influence of housing density.
Conducted a geographic analysis of ESBL-E colonization in humans and animals.
Performed genomic analysis to investigate strain diversity and potential dissemination.
Significant colonization of ESBL-E observed in both humans and animals.
Geographic analysis suggests human impact on animal colonization without direct transmission.
Genomic findings indicate potential for ESBL-E dissemination over large distances.

Abstract

In the area under study, there is significant colonization of both human and animals by ESBL-E, and a major diversity among the isolated strains. Our geographic analysis suggests a human impact on animal colonization, even though the results do not support direct transmission. Concurrently, genomic analysis suggests the possibility of dissemination over significant distances.

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Spread of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) in the community living spaces of patients identified as ESBL-E carriers: impact of the housing density in an African context

Key Points

Abstract

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