An Ir(III)-based Type I Photosensitizer Triggers Immunogenic Pyroptosis in Prostate Cancer

Key Points

• This research aims to explore how an Ir(III)-based photosensitizer can induce pyroptosis and enhance T cell immunity in prostate cancer.
• Utilized an Ir(III)-based photosensitizer to induce pyroptosis in prostate cancer cells.
• Measured T cell immune responses to assess the immunogenicity of the induced cell death.
• The photosensitizer effectively triggered pyroptosis in cancer cells.
• Induced pyroptosis led to a significant activation of T cell immune responses.