What question did this study set out to answer?

To analyze mortality trends of melanoma in Germany from 2001 to 2020 and explore treatment options for aggressive cases.

April 23, 2026EJC Skin Cancer0 citationsOpen Access

Mortality trends of melanoma in Germany from 2001 to 2020

LNL. NanzUniversity Children's Hospital Tübingen CGC. GarbeBernstein Center for Computational Neuroscience Tübingen ULU. LeiterUniversity Children's Hospital Tübingen

Key Points

To analyze mortality trends of melanoma in Germany from 2001 to 2020 and explore treatment options for aggressive cases.
Analyzed mortality data over two decades.
Evaluated the effectiveness of different treatment modalities, including systemic therapy and radiotherapy.
Assessed outcomes through CT scans and clinical responses.
Notable trends in melanoma mortality rates observed over the specified period.
Combining systemic therapy with radiotherapy suggested for treating locally advanced tumours.
Significant decreases in lymph node metastasis size noted, indicating treatment effectiveness.

Abstract

A forearm tumour before and after 3 months of the treatment.Moreover, a CT scan has shown a significant decrease in the size of lymph node metastasis (picture 2) A CT scan before and during the treatment.and wall chest involvement.On the CT scan in May 2025, we observed a complete response to treatment.The patient has been continuing the treatment for 20 months.Conclusions: There is a lack of data describing the treatment of melanoma with rhabdomyoblastic features.Because of the aggressive nature of the disease, it is worth considering combining systemic therapy with radiotherapy in case of locallyadvanced tumours.

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