What question did this study set out to answer?

The aim is to highlight the overlooked importance of spinal cord MRI metrics in multiple sclerosis trials.

April 23, 2026Multiple Sclerosis Journal1 citationsOpen Access

Spinal cord imaging in multiple sclerosis: A vital component we can no longer overlook

ATAhmad A. ToubasiUniversity of Jordan DLDhairya A. LakhaniWest Virginia University JMJeffrey MooreVanderbilt University Medical Center

Key Points

The aim is to highlight the overlooked importance of spinal cord MRI metrics in multiple sclerosis trials.
Review of existing clinical trial methodologies regarding spinal cord MRI metrics.
Evaluation of the impact of spinal cord disease on disability through imaging standards.
Very few clinical trials currently utilize spinal cord MRI metrics as outcome measures.
Standardizing imaging could enhance the applicability and effectiveness of spinal cord MRI in future trials.

Abstract

A very small proportion of clinical trials have used SC MRI metrics as outcome measures. Given the substantial impact of SC disease on disability, it is essential to standardize SC imaging, post-processing, and analytical methods across centres to enhance the effectiveness and applicability of SC MRI in future clinical trials.

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Cite This Study

Toubasi et al. (Tue,) studied this question.

synapsesocial.com/papers/69e9b8d485696592c86ebe0f https://doi.org/https://doi.org/10.1177/13524585261438770

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