Comparison of Hibiscus sabdariffa L. extract and hydrochlorothiazide as adjuncts to Valsartan in managing hypertension in type 2 diabetic nephropathy: A randomized clinical trial.

Key Points

• The study aims to compare the effectiveness of hibiscus extract and hydrochlorothiazide as adjuncts to valsartan in managing hypertension in type 2 diabetic nephropathy patients.
• Conducted a randomized clinical trial
• Compared hibiscus sabdariffa extract and hydrochlorothiazide in conjunction with valsartan
• Evaluated effects on blood pressure and metabolic parameters
• Hibiscus extract shows potential in modifying renin-angiotensin-aldosterone system activity
• Both treatments help reduce risks of diabetic complications
• Treatment with hibiscus may enhance carbohydrate digestion processes and lipid metabolism