Antioxidant, anti-inflammatory and cytoprotective effects of crocin, a bioactive constituent of saffron, in Alzheimer's and Parkinson's diseases with a focus on molecular mechanisms: A systematic review.

Key Points

• This review aims to evaluate the effects of crocin in the context of Alzheimer's and Parkinson's diseases, focusing on its mechanisms of action.
• Systematic review of existing literature on crocin and its effects on neurodegenerative diseases.
• Analysis of molecular mechanisms involved in crocin's antioxidant and anti-inflammatory activities.
• Evaluation of crocin's cytoprotective properties.
• Crocin shows significant antioxidant and anti-inflammatory effects.
• Evidence supports crocin's role as a neuroprotective agent in Alzheimer's and Parkinson's diseases.
• The findings suggest crocin may be a promising candidate for therapeutic use.