A novel PCL fiber membrane with a gradient structure for guided bone regeneration

Key Points

• To evaluate the effectiveness of a gradient-structured PCL membrane for guided bone regeneration.
• Fabricated gradient-structured PCL membrane using humidity/speed-tunable electrospinning
• Assessed membrane properties such as delamination prevention and cell infiltration capabilities
• The membrane effectively prevents delamination during use
• Demonstrated enhanced cell attachment and infiltration
• Shows potential as a strategy for improving guided bone regeneration outcomes