The Impact of Postoperative Complications After Colon Cancer Surgery on Locoregional Recurrence: A Population-Based Dutch Cohort Study

Key Points

• The aim is to assess how postoperative complications influence locoregional recurrence in colon cancer patients.
• Analyzed a population-based cohort of patients who underwent colon cancer surgery.
• Investigated the impact of various surgical and non-surgical complications on outcomes.
• Examined associations between complications and locoregional recurrence as well as overall survival.
• Postoperative complications significantly increased the risk of locoregional recurrence.
• Anastomotic leakage was the only complication independently associated with locoregional recurrence.
• Both surgical and non-surgical complications negatively affected overall survival.