Recent Advances in Electrochemical Nucleophilic Introduction of Azide and Functionalization

Azides, as multifunctional nitrogen‐containing molecules, are significant precursors in various chemical transformations, especially for the preparation of amines, amides, nitriles, triazoles, tetrazoles, and pyrrolines by subsequent redox, cycloaddition, click chemistry, and rearrangement processes. Organic electrochemistry has garnered increasing attention due to its essential potential to promote the development of sustainable organic synthesis, enabling the new avenues to introduce the azide group or directly realize the functionalization in the past decade. In this review, the research progress on the nucleophilic incorporation and direct functionalization of azide groups through electrochemical methodologies is critically summarized based on the electrophilic species involved. The representative scopes and electrochemical mechanism are emphatically described, aiming to inspire innovations in the development of azide chemistry.