November 20, 2025Open Access
View Full PaperCholesterol management in US adults with ASCVD in the Family Heart Database® during 2022–23: Current state of care and opportunities for improvement
Structured PICO
P
Population
3.6 million US adults with ASCVD in the Family Heart Database® during 2022–23
O
Outcome
Gap between guideline recommended LDL-C management and clinical care
There remains a substantial gap in guideline-recommended LDL-C management among US adults with ASCVD, driven partly by the underutilization of nonstatin therapies.
Abstract
In this cohort of 3.6 million US adults with ASCVD there was a substantial gap between guideline recommended LDL-C management and clinical care. Several factors contributed to this gap including low use of nonstatin LDL-C therapies in this high-risk population.