Incidence and risk factors of vancomycin-associated nephrotoxicity among neonates in the intensive care unit: a retrospective cohort study

Key Points

• This study aims to identify the incidence and risk factors associated with vancomycin-related nephrotoxicity in neonates in the ICU.
• Conducted a retrospective cohort analysis of neonates in the intensive care unit.
• Analyses focused on the correlation between postmenstrual age, weight, and acute kidney injury (AKI).
• Lower postmenstrual age is an independent predictor of vancomycin-associated AKI.
• Increased mortality is linked to lower neonatal weight and AKI, highlighting the need for careful monitoring.