What question did this study set out to answer?

To address the therapeutic challenges posed by Trichophyton indotineae infections and the need for better diagnostic techniques.

May 4, 2026

Therapeutic Challenges in Case of Trichophyton indotineae Dermatophytosis, Singapore, 2025.

Key Points

To address the therapeutic challenges posed by Trichophyton indotineae infections and the need for better diagnostic techniques.
Reported a case of T. indotineae infection in Singapore.
Used combination therapy with anidulafungin and itraconazole after failed azole therapy.
Infection showed limited response to prolonged azole therapy.
Successful resolution achieved only with combination therapy of anidulafungin and itraconazole.
Highlights the need for improved diagnostics in T. indotineae infections.

Abstract

Trichophyton indotineae is an emerging dermatophyte frequently associated with terbinafine resistance. We report a case of recalcitrant T. indotineae infection in Singapore with limited response despite prolonged azole therapy, which only resolved after combination therapy with anidulafungin and itraconazole. This case highlights therapeutic challenges and need for improved diagnostics in T. indotineae infections.

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