Background: Acne vulgaris is a chronic dermatological disease that, beyond its visible cutaneous manifestations, exerts a significant negative impact on psychological well-being. Clinical evidence demonstrates that the persistent nature of this inflammatory condition is directly associated with a heightened susceptibility to clinical depression, anxiety, and body dysmorphic disorder (BDD). This inherent link between skin health and mental state necessitates a comprehensive, integrated approach to patient care. Objective: This narrative review first aims to illuminate the profound psychological dimensions of acne vulgaris—particularly the emotional distress and social isolation experienced by patients. Subsequently, it critically evaluates the role of modern digital health interventions (mHealth, teledermatology, artificial intelligence) in managing this burden and analyzes the dual impact of social media on patients' psychosocial functioning. Methods: A systematic literature search was conducted across primary scientific databases, leading to the selection of 23 peer-reviewed articles. The incorporated studies specifically focused on the psychiatric toll of inflammatory skin diseases, the clinical efficacy of remote care, and the societal implications of emerging digital phenomena in dermatology. Results and Discussion: The synthesized evidence indicates that structured digital tools—most notably internet-delivered cognitive behavioral therapy (ICBT) and mobile applications grounded in self-regulation theory—effectively improve clinical outcomes while restoring patients’ sense of personal control over their condition. Furthermore, while the diagnostic accuracy of artificial intelligence (AI) models continues to evolve, their integration introduces a standardized, data-driven assessment. This emotionless baseline can assist patients in rationalizing their distorted self-image. However, the modern social media landscape exerts a distinctly paradoxical influence. While grassroots initiatives like the "acne positivity" movement actively combat social isolation by fostering peer-support networks, these platforms simultaneously expose vulnerable users to unrealistic aesthetic standards that can exacerbate dysmorphic symptoms. Additionally, this environment is frequently saturated with unverified medical information, predominantly driven by influencers promoting pseudoscientific therapies. Conclusions: To optimize psychodermatological care, healthcare systems must adopt hybrid ("blended care") treatment models that seamlessly integrate traditional in-person consultations with remote digital monitoring, thereby preserving the fundamental physician-patient relationship. Furthermore, the industry requires stricter regulatory oversight of commercial medical applications. It is equally critical to train diagnostic AI algorithms on highly diverse datasets encompassing all skin phototypes to prevent algorithmic bias. Finally, the medical community must establish a proactive online presence to actively counter digital misinformation.
Maciejewska-Gaskoń et al. (Thu,) studied this question.