In vitro and In vivo Inhibition of amyloid β aggregation by a Ru(II)-naphthalene diimide complex

Key Points

• To investigate the inhibition of amyloid β aggregation by a Ru(II)-naphthalene diimide complex.
• Conducted in vitro assays to assess amyloid β aggregation inhibition.
• Performed in vivo experiments to evaluate the complex's effect on amyloid deposits.
• Utilized various biochemical assays to measure molecular interactions.
• The Ru(II)-naphthalene diimide complex significantly inhibited amyloid β aggregation.
• Inhibition observed both in vitro and in vivo supports its potential as a treatment.
• Suggests a possible therapeutic strategy for Alzheimer’s disease by targeting amyloid β.