Leukocyte count, leukocyte-to-platelet ratio, and neutrophil-to-platelet ratio were significantly higher in patients with myocardial infarction compared to non-MI patients presenting with chest pain.
Case-Control (n=120)
Do hemogram-based inflammatory parameters (leukocyte count, leukocyte-to-platelet ratio, neutrophil-to-platelet ratio) accurately identify myocardial infarction in patients presenting to the emergency department with chest pain?
Hemogram-based inflammatory parameters, including leukocyte-to-platelet and neutrophil-to-platelet ratios, are significantly elevated in patients with myocardial infarction and may aid in diagnostic evaluation in the emergency department.
AimWe aimed to evaluate the diagnostic value of hemogram-based inflammatory parameters particularly leukocyte, leukocyte-to-platelet ratio, and neutrophil-to-platelet ratio in identifying myocardial infarction among patients presenting to the emergency department with chest pain.Materials and Methods:A total of 60 myocardial infarction and 60 non- myocardial infarction patients aged over 18 years who presented to the emergency department with chest pain between January and February 2025 were retrospectively analyzed. Hemogram, biochemistry, electrocardiography, and creatine kinase-MB values were evaluated. leukocyte, , leukocyte-to-platelet and neutrophil-to-platelet ratios were compared between the two groups. The discriminatory performance of these parameters was assessed using Receiver Operating Characteristic analysis, and optimal cutoff values were determined using the Youden index.Results:Glucose, creatine kinase-MB, leukocyte, neutrophil count leukocyte-to-platelet ratio, and neutrophil-to-platelet ratio levels were significantly higher in the myocardial infarction group compared with the control group (p
Yumrutepe et al. (Sat,) conducted a case-control in Myocardial infarction (n=120). Hemogram-based inflammatory parameters vs. Non-myocardial infarction was evaluated on Discriminatory performance of hemogram parameters for myocardial infarction. Leukocyte count, leukocyte-to-platelet ratio, and neutrophil-to-platelet ratio were significantly higher in patients with myocardial infarction compared to non-MI patients presenting with chest pain.
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