Abstract Limb-girdle muscular dystrophy (LGMD) is a progressive neuromuscular disorder characterised by proximal muscle weakness, often exacerbated by obesity-related deconditioning. We report the outcomes of an intensive, individualised inpatient rehabilitation programme in a 23-year-old male with genetically confirmed LGMD and Class II obesity (body mass index 37.58 kg/m 2 ) who presented with severe functional decline. The multidisciplinary intervention included tailored physiotherapy, ambulation training, respiratory exercises, occupational therapy, nutritional optimisation, psychological counselling and adaptive equipment training. Over 45 days, significant functional improvement was observed: The functional independence measure motor subscore increased from 78 to 91, 6-min walk distance improved from 120 m to 850 m and the Fatigue Severity Scale score decreased from 53 to 18. Muscle strength and endurance also improved, accompanied by a 13 kg weight reduction. This case highlights that intensive, individualised rehabilitation incorporating weight management can yield meaningful functional recovery in LGMD complicated by obesity, emphasising the value of early multidisciplinary intervention.
Selvaraj et al. (Mon,) studied this question.