Does hemodiafiltration compared to hemodialysis with cooled dialysate improve cardiovascular responses assessed by intradialytic MRI in dialysis patients?
Hemodiafiltration and hemodialysis with cooled dialysate produce similar cardiovascular responses, including decreased systolic function and myocardial perfusion during treatment.
=0.29), and both modalities provided a similar degree of cooling. All measures of systolic contractile function fell during HD and HDF, with partial recovery after dialysis. All patients experienced some degree of segmental left ventricular dysfunction, with severity proportional to ultrafiltration rate and BP reduction. Myocardial perfusion decreased significantly during HD and HDF. Treatment modality did not influence any of the cardiovascular responses to dialysis. In conclusion, in this randomized, crossover study, there was no significant difference in the cardiovascular response to HDF or HD with cooled dialysate as assessed with intradialytic MRI.
Buchanan et al. (Thu,) studied this question.
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