Fixed Drug Eruptions to Antihistamines with Challenge Test to Generate Safe List of Antihistamines

Key Points

• The aim is to identify safe antihistamines through challenge testing in patients with fixed drug eruptions.
• Conducted a challenge test with various antihistamines in patients with fixed drug eruptions.
• Evaluated histopathological changes in skin samples post-exposure to antihistamines.
• Identified certain antihistamines that do not trigger fixed drug eruptions.
• Histopathological analysis confirmed specific changes associated with drug hypersensitivity.