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CD1d knockout swine are permissive to African swine fever virus genotype II infection | Synapse

May 10, 2026Emerging Microbes & Infections0 citationsOpen Access

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CD1d knockout swine are permissive to African swine fever virus genotype II infection

DMDaniel MaddenKansas State University JTJessie D. TrujilloKansas State University SES. ElangoKansas State University

Key Points

Investigating the susceptibility of CD1d knockout swine to infection by African swine fever virus genotype II.
Observed CD1d knockout piglets for resistance to virulent genotype II ASFV infection.
Conducted infection experiments to assess immune response in knockout piglets.
KO piglets exhibited no resistance to virulent genotype II ASFV infection.
Infected knockout swine demonstrated a high rate of infection.

Abstract

KO piglets possess no resistance to virulent genotype II ASFV infection.

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Cite This Study

Madden et al. (Fri,) studied this question.

synapsesocial.com/papers/6a002222c8f74e3340f9d1ce https://doi.org/https://doi.org/10.1080/22221751.2026.2671519