What are the risk factors for cardiac adverse events and mortality in patients with unilateral breast cancer receiving curative radiotherapy?
In patients treated with curative radiotherapy for unilateral breast cancer, heart failure and atrial fibrillation are common within the first decade, highlighting the need for early cardio-oncological follow-up.
<0.001). Conclusions Ten-year mortality following curative treatment for unilateral BC was mainly cancer related, but heart failure and atrial fibrillation/flutter were already common in the first decade following irradiation. Mean heart dose, pre-existing cardiovascular diseases, and Mayo Clinic Cardiotoxicity Risk Score were risk factors for cardiac adverse events. These results suggest a need for early dedicated cardio-oncological follow-up after radiotherapy.
Jacobs et al. (Fri,) studied this question.