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Abstract An unprecedented metal‐free approach to polyheterocycles bearing furoquinoline and C2‐maleimide‐substituted quinoline has been developed with easily available quinoline N ‐oxides and maleimides via tandem reactions mediated by I 2 , including iodization, 3+2 cycloaddition and nucleophilic addition reactions. I 2 acts as a halogenating agent to promote the subsequent 1,5‐sigma rearrangement. Two C−O bonds, three C−C bonds and a quaternary carbon center were formed in “one pot” manner. magnified image
Du et al. (Fri,) studied this question.
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