Introduction: Acute osteomyelitis (AOM) is a common pediatric infection; however, its association with deep vein thrombosis (DVT) is rare and often underdiagnosed due to overlapping symptoms. Case Report: We report three pediatric cases (mean age 9.3 years) of femoral AOM complicated by DVT, all due to methicillin-resistant Staphylococcus aureus (MRSA). Fever, limb pain, and swelling were the presenting triad in all patients. Magnetic resonance imaging confirmed osteomyelitis with abscess, and Doppler ultrasound or computed tomography venogram detected DVT. Management included surgical drainage with cortical decompression and anticoagulation therapy. All patients achieved complete recovery within 10-12 months. Conclusion: Severe femoral osteomyelitis, particularly when MRSA-positive, should prompt clinicians to consider concurrent DVT. Early combined imaging and intervention can prevent serious complications and ensure optimal functional outcomes.
Mahamani et al. (Thu,) studied this question.