OBJECTIVES: Various radiation dosing regimens exist due to tumor size, location, and patient preference. This study evaluated the long-term outcomes of patients with benign meningiomas treated with hSRT at our institution. METHODS: This is a retrospective review of all patients diagnosed with meningioma at our institution who received hSRT (5 fractions). Clinical data, including tumor location, size, prior treatments, demographics, radiation dosimetric information, tumor response, and survival were collected. Kaplan-Meier curves were used to assess local control. Acute and late toxicities were evaluated. Patients were included for analysis if they had at least one post-treatment MRI following therapy. RESULTS: =0.6, p=0.73). CONCLUSIONS: The SRT regimen of 25 Gy in 5 fractions effectively achieves local control and safety in benign meningiomas. These findings highlight the need for further clinical studies to better understand WHO grade 1 meningiomas.
Shah et al. (Fri,) studied this question.