Chronic fructose overload induced severe baroreflex impairment (r = -0.85) and cardiometabolic dysfunctions in rats, with compensatory parasympathetic enhancement observed in SAD rats.
Chronic fructose overload impairs baroreflex function and causes cardiometabolic dysfunction in rats, highlighting vagal modulation as a potential therapeutic target.
= -0.85). Our results showed that: (1) chronic fructose overload induced severe baroreflex impairment, i.e. in a similar magnitude to that observed in SAD rats, which is accompanied by cardiometabolic dysfunctions; (2) the compensatory enhancement in parasympathetic function in SAD rats submitted to fructose intake may point out the possibility of use of approaches that improve vagal function as therapeutic target to attenuate fructose-induced cardiometabolic dysfunctions.
Santos et al. (Mon,) conducted a other in Fructose-induced cardiometabolic dysfunctions. Chronic fructose overload was evaluated on Baroreflex impairment and cardiometabolic dysfunctions. Chronic fructose overload induced severe baroreflex impairment (r = -0.85) and cardiometabolic dysfunctions in rats, with compensatory parasympathetic enhancement observed in SAD rats.
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