Cloth-covered Starr-Edwards prostheses demonstrated moderate aortic systolic pressure gradients (mean 41 mm Hg) and mitral diastolic gradients (mean 9.4 mm Hg), comparing unfavorably with older models.
Observational (n=22)
What are the hemodynamic characteristics of the cloth-covered Starr-Edwards valve prosthesis in patients requiring valve replacement?
The cloth-covered Starr-Edwards valve prosthesis exhibits unfavorable hemodynamic characteristics, including functional stenosis, compared to previous models.
Hemodynamic studies were performed in 22 patients three to ten months after insertion of cloth-covered Starr-Edwards prostheses. The aortic valve was replaced in ten patients, the mitral in ten, and both valves in two. Moderate aortic systolic pressure gradients were found in all patients with aortic prostheses (range 17 to 68 mm Hg, mean 41 mm Hg), and the calculated valve orifice areas were small (average 0.92 cm 2 ). Mitral diastolic pressure gradients in those with mitral prostheses averaged 9.4 mm Hg and were associated with persistently elevated left atrial pressure (average 18 mm Hg). These findings compare unfavorably with the hemodynamic characteristics of previous Starr-Edwards prostheses. Factors contributing to the functional stenosis appear to be smaller valve orifices and turbulent blood flow generated by the coarse cloth surfaces and a shorter excursion of the ball.
Kloster et al. (Thu,) conducted a observational in Valvular heart disease requiring prosthesis (n=22). Cloth-covered Starr-Edwards valve prosthesis vs. Previous Starr-Edwards prostheses (historical) was evaluated on Hemodynamic characteristics (aortic systolic and mitral diastolic pressure gradients). Cloth-covered Starr-Edwards prostheses demonstrated moderate aortic systolic pressure gradients (mean 41 mm Hg) and mitral diastolic gradients (mean 9.4 mm Hg), comparing unfavorably with older models.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: