Duralabharishtam is an important Ayurvedic formulation widely used in the management of various conditions such as Pandu (anaemia), Arsha (haemorrhoids), Pleeharoga (spleen disorders), Gulma (abdominal lumps), Hrudrog (heart diseases), Grahani (malabsorption syndrome), Shotha (swelling), Aruchi (loss of appetite), Granthi (cysts), Arbuda (tumours/cancer) and Kushtha (skin diseases). Classical Ayurvedic literature mentions eight references of this formulation under two variant names, Sharkarasav and Dwitiya Phalarishtam. Among these, the formulation described in Ashtanga Hrudayam is most widely accepted and commonly used in clinical practice and in pharmaceutical preparations. The standard formulation consists of nine ingredients of plant origin. The present study aims to critically review this formulation. Based on the analysis of the pharmacological properties of its ingredients, it can be inferred that Duralabharishtam may be effective in all the above-mentioned indications. Among the five Pathabheda of mentioned formulation, there is a need to standardize each Pathbheda and clinically evaluate them according to Phalshruti for their effective use in practice. Pharmacologically, it supports digestion, metabolism, bowel regulation, and has anti-parasitic and anti-inflammatory effects. It is mainly used in gastro-intestinal and metabolic disorders like Arsha, Grahani, Pandu. Limited research suggests benefits in conditions such as celiac disease and haemorrhoids, through the evidence is not extensive. Further standardization, quality control, and large-scale clinical studies are needed to validate its efficacy.
1*Dr. Supriya Bansode, 2Dr. Shardul Chavan, 3Dr. Anju Sreedharan (Sat,) studied this question.