Pulse pressures of 50-59, 60-69, and 90+ were associated with a higher risk of dementia in women aged ≥60 years compared to pulse pressure <50 (HRs 1.14, 1.22, and 1.03, respectively).
Cohort (n=149,663)
Does higher pulse pressure increase the risk of dementia onset in adults aged ≥60 years?
Higher pulse pressure is associated with an elevated risk of dementia in elderly women, particularly those on Medicaid and from rural regions.
Effect estimate: HR 1.14, 1.22, and 1.03
Objective: There is paucity of studies on the association between pulse pressure and the development of dementia, although this association has already been established. This study aimed at investigating the association between pulse pressure and the onset of dementia. Methods: We used the South Korean National Health Insurance Service claims cohort data to select 149,663 patients without dementia aged ≥60 years. We calculated adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for dementia using Cox proportional hazard models according to a pulse pressure classification (60 years, particularly those on Medicaid and from rural regions, possibly due to their inability to access hypertension and other medical treatment. The establishment of dementia indicators will help to guide future health policies for the prevention of dementia.
Jung et al. (Wed,) conducted a cohort in Dementia (n=149,663). Pulse pressure vs. Pulse pressure <50 was evaluated on Onset of dementia (HR 1.14, 1.22, and 1.03). Pulse pressures of 50-59, 60-69, and 90+ were associated with a higher risk of dementia in women aged ≥60 years compared to pulse pressure <50 (HRs 1.14, 1.22, and 1.03, respectively).