A coronary artery calcium score of 400 or higher was an independent predictor of major adverse cardiovascular events (OR 1.007) in patients with stable coronary artery disease.
Cohort (n=435)
No
Does a high coronary artery calcium score (≥ 400) predict major adverse cardiovascular events in patients with stable ischemic heart disease?
A coronary artery calcium score of 400 or higher is an independent predictor of major adverse cardiovascular events in patients with stable ischemic heart disease over a 2-year period.
Effect estimate: OR 1.007 (95% CI 1.005-1.009)
p-value: p=0.001
BACKGROUND: Coronary artery atherosclerosis and calcification are the precursors to the development of coronary artery disease and its complications. Coronary artery calcium scoring (CACS) is useful as a risk-stratification tool in coronary artery disease. OBJECTIVE: The current study was designed to identify the relationship between CACS and major adverse cardiovascular outcomes in patients with stable coronary artery disease. METHODS: The study was conducted on 435 patients with stable ischemic heart disease. The patients were classified into two groups according to their coronary artery calcium score (CACS): group I (n = 220 patients), whose calcium score was mild to moderate ( 10, CACS ≥ 400, body mass index ≥ 30 kg/m2, and the proximal lesions of the vessels were the independent risk factors for major cardiac events. CONCLUSION: The coronary calcium score is a distinct feature of coronary atherosclerosis, and a score of 400 or higher is a reliable, noninvasive predictor of the progression of coronary artery diseases and their consequences, including MACE.
Elnagar et al. (Thu,) conducted a cohort in Stable coronary artery disease (n=435). High coronary artery calcium score (≥ 400) vs. Mild to moderate coronary artery calcium score (< 400) was evaluated on Major adverse cardiovascular events (MACE) (OR 1.007, 95% CI 1.005-1.009, p=0.001). A coronary artery calcium score of 400 or higher was an independent predictor of major adverse cardiovascular events (OR 1.007) in patients with stable coronary artery disease.