Medical treatment in Japanese patients with coronary artery disease resulted in a 9.8% rate of cardiac death and/or non-fatal myocardial infarction over an average follow-up of 49 months.
Cohort (n=491)
Yes
What is the incidence of major cardiac events and its risk factors in medically treated Japanese patients with coronary artery disease?
In Japanese patients with coronary artery disease receiving medical therapy between 1973 and 1985, the rate of cardiac death or non-fatal MI was 9.8% over 49 months, which was more favorable than contemporary US reports.
In the cooperative, multi-center trial, 491 medically treated patients with coronary artery disease were thoroughly assessed and followed for an average of 49 months. The rate of cardiac death and/or non-fatal myocardial infarction was 9.8%; 64% of cardiac events were fatal. Three factors, such as number of diseased coronary arteries, other diseased organs and the cardiothoracic ratio, contributed significantly to the evolution of cardiac events. The outcome of cardiac events in Japan in the period from 1973 to 1985 in patients with coronary artery disease was more favorable than those reported recently in the United States. The results of this study will serve as a control data base for further studies in Japan.
Hosoda et al. (Mon,) conducted a cohort in Coronary artery disease (n=491). Medical treatment was evaluated on Cardiac death and/or non-fatal myocardial infarction. Medical treatment in Japanese patients with coronary artery disease resulted in a 9.8% rate of cardiac death and/or non-fatal myocardial infarction over an average follow-up of 49 months.
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