Staging Prostatic Cancer: A Different Distribution

No AccessJournal of Urology1 Sep 1979Staging Prostatic Cancer: A Different Distribution Robert E. Donohue, H. Earl Fauver, John A. Whitesel, and Ronald R. Pfister Robert E. DonohueRobert E. Donohue More articles by this author , H. Earl FauverH. Earl Fauver Current address: Fitzsimons Army Medical Center, Aurora, Colorado 80340. More articles by this author , John A. WhiteselJohn A. Whitesel Current address: 2020 Wadsworth Ave., Lakewood, Colorado 80215. More articles by this author , and Ronald R. PfisterRonald R. Pfister More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)56389-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail A review of 300 recent cases of prostatic adenocarcinoma and use of current staging methods revealed a marked change in the distribution of the various stages of the disease from previous classical reports. Stage A disease, the incidental carcinoma, now assumes a significant proportion of new cases (37 per cent) and full staging procedures must be done at least in all A2 cases (13 per cent). This is especially true in those patients with higher grade lesions. One of the challenges facing urologists in the future is to detect which of these patients with stage A2 disease are at greater risk and to investigate the use of early therapy to determine whether the natural history of this disease can be affected. Stage B disease, clinical B1 disease, often pathologically B2, C or Dl, may be curable by other than radical prostatectomy with its impotence and threat to continence. Controlled, randomized studies are needed to establish the natural history of the disease now since its stage is more finely and accurately determined and to compare the various treatment modalities, that is radical prostatectomy, external beam radiotherapy and implantation therapy with that history. B2 disease, surgically less curable with a higher percentage of cases revealing local lymph node spread at staging lymphadenectomy, also must have controlled studies. Stage C disease (50 per cent of which becomes stage Dl with pelvic lymphadenectomy), usually surgically incurable, must be treated and evaluated with modalities other than an operation alone also to see if increased survival, free of disease, can be achieved. © 1979 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByGohagan J, Prorok P, Kramer B and Cornett J (2018) Prostate Cancer Screening in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial of the National Cancer InstituteJournal of Urology, VOL. 152, NO. 5 Part 2, (1905-1909), Online publication date: 1-Nov-1994.Partin A, Walsh A, Pitcock R, Mohler J, Epstein J and Coffey D (2018) A Comparison of Nuclear Morphometry and Gleason Grade as a Predictor of Prognosis in Stage A2 Prostate Cancer: A Critical AnalysisJournal of Urology, VOL. 142, NO. 5, (1254-1258), Online publication date: 1-Nov-1989.Thompson I, Rounder J, Teague J, Peek M and Spence C (2018) Impact of Routine Screening for Adenocarcinoma of the Prostate on Stage DistributionJournal of Urology, VOL. 137, NO. 3, (424-426), Online publication date: 1-Mar-1987.Carroll P, Leitner T, Yen T, Watson R and Williams R (2018) Incidental Carcinoma of the Prostate: Significance of Staging Transurethral ResectionJournal of Urology, VOL. 133, NO. 5, (811-814), Online publication date: 1-May-1985.Parfitt H, Smith J, Seaman J and Middleton R (2018) Surgical Treatment of Stage A2 Prostatic Carcinoma: Significance of Tumor Grade and ExtentJournal of Urology, VOL. 129, NO. 4, (763-765), Online publication date: 1-Apr-1983.Elder J, Jewett H and Walsh P (2018) Radical Perineal Prostatectomy for Clinical Stage B2 Carcinoma of the ProstateJournal of Urology, VOL. 127, NO. 4, (704-706), Online publication date: 1-Apr-1982.Paulson D (2018) Editorial CommentJournal of Urology, VOL. 127, NO. 4, (706-706), Online publication date: 1-Apr-1982. Volume 122Issue 3September 1979Page: 327-329 Advertisement Copyright & Permissions© 1979 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Robert E. Donohue More articles by this author H. Earl Fauver Current address: Fitzsimons Army Medical Center, Aurora, Colorado 80340. More articles by this author John A. Whitesel Current address: 2020 Wadsworth Ave., Lakewood, Colorado 80215. More articles by this author Ronald R. Pfister More articles by this author Expand All Advertisement PDF DownloadLoading ...