What question did this study set out to answer?

This work aims to define K_psych as a modular Hamiltonian integrating various psychiatric factors and their interactions.

May 21, 2026Open Access

ITU Tier 1+ #7: Psychiatric Information Theory (Kₚsych)

Key Points

This work aims to define K_psych as a modular Hamiltonian integrating various psychiatric factors and their interactions.
Defines K_psych using operator-algebraic methods on various interrelated fields
Explores numerical results related to psychiatric conditions
Analyzes treatment efficacy of substances like ketamine, psilocybin, and MDMA-AT.
Depression prevalence estimated at 280 million according to WHO
Linear predictions include 20% suicide rate reduction by 2030
Notable treatments include non-D2 antipsychotic KarXT in 2024.

Abstract

Tier 1+ Pass-1. 5 paper 7 of 45. ITU-derived psychiatry on neurotransmitter + circuit + behavior + env + genetics. Defines Kₚsych = -log ρₚsych as the operator-algebraic modular Hamiltonian on Hₙeurotransmitter ⊗ Hcircuit ⊗ Hbehavior ⊗ Hₑnvironment ⊗ Hgenetics. Kₚsych inherits from KQG via the CLPW 2023 type II crossed-product specialised to this scale. Numerical results. Depression prevalence WHO 280M, SSRI Prozac 1987, MDMA-AT Lykos FDA rejected 2024. 8. 9, Cobenfy KarXT BMS 2024. 9. 27 first non-D2 antipsychotic. Topics covered. Psychiatric diagnosis DSM-5-TR 2022, ketamine/esketamine 2019, psilocybin Compass Phase 3, MDMA-AT 2024. 8. 9 rejected, RDoC NIMH 2010. 45-vertex polytope #7 top couplings: #1 AI (0. 92), #5 Cancer (0. 85), #27 Microbiome (0. 85), #38 Anthro (0. 85). Ten falsifiable predictions: Pₐvg=0. 68: arXiv 2026 (0. 90 S), Psilocybin FDA approval 2027 (0. 65 M), Suicide rate reduction 20% by 2030 (0. 45 W). Pass-2 roadmap: ~1. 8M: Psych analytics (600K) + Lean Mathlib (200K) + Trial partnerships (1M). Copyright © 2026 Munehiro Terada / Roboken. Licensed under CC-BY-4. 0.

ITU Tier 1+ #7: Psychiatric Information Theory (Kₚsych)

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Abstract

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