Application of the ESGDHF Doppler-echocardiographic criteria confirmed diastolic heart failure in only 43% of heart failure admissions with preserved systolic function.
Observational (n=210)
What proportion of patients admitted with heart failure and preserved systolic function meet ESGDHF Doppler-echocardiographic criteria for diastolic heart failure?
Less than half of patients admitted with heart failure and preserved systolic function met established Doppler-echocardiographic criteria for diastolic heart failure, suggesting alternative or unclear pathophysiological mechanisms in the majority.
Many patients admitted to hospital with heart failure have preserved left ventricular (LV) systolic function. The incidence of isolated diastolic dysfunction as a cause of such admission remains unclear. We aimed to examine diastolic function in unselected admissions from the community with heart failure using the European Study Group on Diastolic Heart Failure (ESGDHF) Doppler-echocardiographic indices of diastolic dysfunction. Primary heart failure was confirmed in 210 of 309 sequential admissions with suspected heart failure. Doppler echocardiography was used to assess left ventricular ejection fraction, wall thickness and parameters of diastolic function including E:A ratio, E-wave deceleration time and isovolumic relaxation time. Of 210 patients studied (118 female), ejection fraction was 45% and no other relevant abnormality. Twenty were in atrial fibrillation. E-wave deceleration time was >280 ms in 42%. E:A was reversed in 30 of 36 patients in sinus rhythm, but only seven met the ESGDHF criterion of E:A105 ms in 38%. Wall thickness was increased in 75% of cases. The ESGDHF Doppler-echocardiographic criteria for diastolic heart failure were fulfilled in 43%. In clinically confirmed heart failure, 27% of patients had preserved systolic function and no significant valvular disease. Only 43% of this group had confirmed diastolic heart failure by these ESGDHF criteria. The pathophysiological basis of the syndrome in the remaining 57% remains unclear.
Cahill et al. (Thu,) conducted a observational in Heart failure with preserved systolic function (n=210). Doppler-echocardiography (ESGDHF criteria) was evaluated on Fulfillment of ESGDHF criteria for diastolic heart failure. Application of the ESGDHF Doppler-echocardiographic criteria confirmed diastolic heart failure in only 43% of heart failure admissions with preserved systolic function.