A novel human picornavirus, provisionally named Saffold virus (SAF-V), was discovered and sequenced from a stool sample of an 8-month-old patient presenting with fever of unknown origin.
Case Report (n=1)
No
A novel human picornavirus belonging to the Cardiovirus genus was discovered in an infant presenting with fever of unknown origin.
Fever of unknown origin (FUO) is a serious problem in the United States. An unidentified agent was cultured from the stool of an infant who presented with FUO. This virus showed growth in HFDK cells and suckling mice. Using DNase sequence-independent single-primer amplification, we identified several nucleotide sequences with a high homology to Theiler's murine encephalomyelitis virus. Nearly full-length viral genome sequencing and phylogenetic analysis demonstrate that this virus is a member of the Cardiovirus genus of the Picornaviridae family.
Jones et al. (Thu,) conducted a case report in Fever of unknown origin (FUO) (n=1). Viral isolation and sequencing was evaluated on Identification of viral agent. A novel human picornavirus, provisionally named Saffold virus (SAF-V), was discovered and sequenced from a stool sample of an 8-month-old patient presenting with fever of unknown origin.
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