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Reproducibility is the cornerstone of science. If an effect is reliable, any competent researcher should be able to obtain it when using the same procedures with adequate statistical power. Two of the articles in this special section question the value of direct replication by other laboratories. In this commentary, I discuss the problematic implications of some of their assumptions and argue that direct replication by multiple laboratories is the only way to verify the reliability of an effect.
Daniel J. Simons (Wed,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: