What does this research mean for the field?

Patients with Ewing's sarcoma present with distinct clinical features at admission and undergo varying treatment courses involving external radiation, radical surgery, or combined therapies. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 2, 1953

Ewing's Sarcoma

Structured PICO

Population

50 patients with histologically proved Ewing sarcoma treated at the Massachusetts General Hospital from 1930 through 1952

Intervention

External radiation alone (n=36), radical surgery (n=10), or surgery followed by x-ray therapy (n=4)

An early case series analyzing the treatment and outcomes of 50 patients with Ewing's sarcoma at a single institution between 1930 and 1952.

Abstract

EWING'S sarcoma was first described by James Ewing in 1921.1 , 2 Since then a voluminous literature regarding this interesting disease has appeared. The pathogenesis, histology, clinical features, and roentgenographic appearance have been extensively studied.3 4 5 6 7 8 9 The purpose of the present investigation is to analyze a group of patients treated at the Massachusetts General Hospital from 1930 through 1952 inclusive.Fifty cases of histologically proved Ewing sarcoma form this group, 36 patients being treated by external radiation alone, 10 by radical surgery, and 4 by surgery followed by x-ray therapy. Of the 36 given radiation alone, 22 at the time of admission showed . . .

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