Monotherapy was the leading trend for antihypertensive therapy (78.32%), with nonselective beta-blockers being the most frequently prescribed class (39.36%) and propranolol the most cost-effective.
Cohort
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What are the prescription patterns, utilization, and cost-effectiveness of antihypertensive medications in a private hospital in Saudi Arabia?
Antihypertensive prescription patterns in a Saudi Arabian private hospital largely adhered to JNC 8 guidelines, with monotherapy being the predominant strategy and propranolol identified as the most cost-effective agent.
Abstract Objectives Mentioned study is carried out to assess the prescription pattern, utilization of drug and cost analysis of antihypertensive medications used in the treatment of hypertension in a private hospital in Saudi Arabia. Methods A retrospective cohort study was carried out in a private hospital in Saudi Arabia. Cost analysis and patterns of outpatient and inpatient antihypertensive drugs used among hypertensive patients between 1 January 2019 and 31 December 2019 were investigated, including incidence, prevalence, duration of use of therapy, class of antihypertensive drugs and therapy for cost-effective use. Key findings Monotherapy (78.32%) was leading trends of antihypertensive therapy that followed fixed dose combination with or without multidrug therapy (21.68%). The most frequent antihypertensive class to be prescribed was nonselective beta-blockers (39.36%) followed by calcium channel blockers (16.51%). The status in terms of cost utilized average per unit was the highest for telmisartan (3.371 (0.90) SR (USD)). The propranolol was most cost-effective (average cost per unit 1.43 (0.38) SR) in relative to the other antihypertensive prescribed. Conclusion Our study suggested that the prescription pattern of drugs used for the treatment of hypertension adhered with the JNC 8 guidelines. Monotherapy was reliably more recommended in the initial stages of hypertension. Higher percentage of patients (78.32%) was found to be on monotherapy. The Saudi Food and Drug Authority (SFDA) has overwhelmed for fixation of prices of drugs.
Mohammad Daud Ali (Sun,) conducted a cohort in Hypertension. Antihypertensive drug therapy was evaluated on Prescription pattern, utilization of drug and cost analysis. Monotherapy was the leading trend for antihypertensive therapy (78.32%), with nonselective beta-blockers being the most frequently prescribed class (39.36%) and propranolol the most cost-effective.
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