Catheter-based device therapy for periprosthetic paravalvular regurgitation is reviewed, detailing current knowledge on pathophysiology, imaging modalities, management principles, and clinical outcomes.
This review summarizes the pathophysiology, imaging, and catheter-based device management of periprosthetic paravalvular regurgitation.
Periprosthetic paravalvular regurgitation is an important sequel associated with prosthetic valves whether implanted surgically or via transcatheter approach. They can remain clinically silent or manifest as clinical heart failure, intravascular hemolysis or a combination of both. Periprosthetic defects are becoming increasingly recognized as a source of morbidity and mortality in patients with prosthetic heart valves and in the last few years, the management of this condition has evolved. This review aims to address the current knowledge on the pathophysiology, imaging modalities and management of these defects. It further details the principles, methodology and outcomes of catheter-based device therapy of periprosthetic paravalvular defects.
Ghimire et al. (Tue,) conducted a review in Periprosthetic paravalvular regurgitation. Catheter-based device therapy was evaluated. Catheter-based device therapy for periprosthetic paravalvular regurgitation is reviewed, detailing current knowledge on pathophysiology, imaging modalities, management principles, and clinical outcomes.