Impact of remote symptom monitoring program on payor-specific healthcare costs.

1632 Background: Remote symptom monitoring (RSM) programs are currently being implemented across oncology practices nationwide; however, the impact of RSM on costs by payor has been understudied. Methods: This is a secondary analysis of a hybrid implementation-effectiveness trial of electronic, patient reported outcome-based RSM for patients with cancer initiating systemic therapy (May 2021-May 2024). Differences in costs for healthcare services for RSM-enrolled patients were compared to historical controls. Outcomes included overall, monthly, payor-, and service-specific costs of care received at 3 and 6 months after RSM-enrollment date or initiation of systemic therapy for controls. Adjusted generalized linear models estimated predicted mean costs, mean cost ratios (MR) and 95% confidence intervals (CIs) for RSM-enrolled patients versus controls. Results: Patients receiving RSM (n=968) were 25% Black, 44% privately insured, and 27% living in a highly disadvantaged neighborhood. Historical controls (n=3, 488) were demographically similar. Though non-statistically significant, RSM enrolled patients had 5% lower mean costs 3 months post-index date compared to historical controls (MR 0. 95, 95% CI 0. 78-1. 16), translating to an estimated cost savings of 1, 347 per patient (95% CI -3, 596, 6, 290). Medicare Fee-for-Service (FFS) beneficiaries showed the greatest, though non-statistically significant, cost reductions, with RSM FFS beneficiaries having 10% lower costs than FFS controls (MR 0. 90, 95% CI 0. 67-1. 19) at 3 months post-index date. Though non-statically significant, RSM-enrolled patients had 23% lower costs for radiation, 14% lower inpatient costs, 9% lower costs for labs, scans, or tests, and 2% lower outpatient costs compared to controls at 3 months post-index date. At one-month post-index date, RSM enrolled patients had statistically significantly lower payor costs compared to controls (11, 849 95% CI 9, 364-14, 335 vs. 15, 706 14, 291-17, 121; p=. 004). Costs for RSM enrolled patients and controls were similar two to six-months post-index date. Conclusions: We observed payor cost savings of 1, 347 in the 3 months of RSM enrollment compared to controls. As the largest payor cost differences were seen for Medicare FFS beneficiaries, our results suggest RSM may address a gap in the provision of care coordination to patients not offered these services through their insurer. Cost savings were most prominent within the first month of treatment initiation; thus, RSM may aid in reducing acute care needs and optimizing resource utilization for patients with cancer. Our results support future research in potential risk-stratification methods to improve RSM engagement and delivery to reduce costs and improve outcomes for patients with cancer.