What is the incidence of congenital cardiovascular malformations in children of parents operated on for congenital cardiovascular malformations?
Children of parents operated on for congenital cardiovascular malformations have a 4.9% incidence of congenital cardiovascular malformations, often matching the parent's specific defect.
The incidence of congenital cardiovascular malformation was studied in 246 children of 166 index patients who had been operated upon for this. Twelve children were affected (4 . 9%). More than half of these had the same malformation as the parent. The incidence of other extracardiac congenital abnormalities did not exceed that recorded in Hungary for the population in general.
Czeizel et al. (Mon,) studied this question.