Iron replacement in patients with heart failure with reduced ejection fraction improves symptoms and exercise capacity.
Does iron replacement improve symptoms and exercise capacity in patients with heart failure and iron deficiency?
This review highlights the clinical relevance of iron deficiency in heart failure and summarizes evidence that iron replacement improves symptoms and exercise capacity in HFrEF.
Iron deficiency (ID) is a commonly present co-morbidity in patients with heart failure (HF). In iron deficient but otherwise healthy individuals, correction of ID restores exercise capacity and endurance regardless of the presence of anaemia. Recently, iron replacement in patients with HF with reduced ejection fraction has been shown to improve symptoms and exercise capacity. This article reviews the clinical relevance of ID in HF and evidence for iron replacement.
Fitzsimons et al. (Thu,) conducted a review in Heart failure with iron deficiency. Iron replacement was evaluated. Iron replacement in patients with heart failure with reduced ejection fraction improves symptoms and exercise capacity.