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SUMMARY: Sodium chloride decreased the maximum specific growth rate of Saccharomyces cerevisiae. Chemostat experiments showed this to be largely due to an increased requirement for energy-yielding substrate, apparently linked to maintenance and leading to a decrease in the yield. The increased maintenance requirement is probably concerned with maintaining an intracellular Na+ concentration ten times lower than the extracellular concentration. NaCl caused much higher concentrations of glucose to be required to maintain any particular glucose-uptake rate; it also increased the production of glycerol.
T. G. Watson (Sun,) studied this question.
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