Non-invasive in vivo determination of body surface and epicardial geometries for electrocardiographic imaging

The inverse problem in electrocardiography involves determining, noninvasively, epicardial potentials and activation isochrones from measured body surface potentials. Although much theoretical work and some preliminary clinical work has been done in this area. One major obstacle to bringing this technique into the clinical arena involves determining, noninvasively, body surface and epicardial surface geometry. Clinical procedures coupling body surface potential mapping (BSPM) with computer tomography (CT)-yielded body surface and epicardial geometries, as well as BSPM electrode position, in six healthy volunteers, accurately and reproducibly. As part of these procedures, CT scans localized electrode position on the body surface of a 224 electrode BSPM vest.>