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Serum protein electrophoresis and typing of monoclonal components (MCs) are routine but time-consuming and technically demanding assays. We evaluated capillary electrophoresis (Paragon CZE 2000) for automation of the two assays. CZE and cellulose acetate electrophoresis gave similar data on 794 samples. Within-run and between-run CVs were 10 g/L; only 50% of MCs that could not be quantified by densitometric scan were typed.
Bienvenu et al. (Sun,) studied this question.