Doppler echocardiography measurement of systolic pulmonary artery pressure correlated strongly with invasive right heart catheterization in patients with severe aortic stenosis (r=0.820, P<0.0001).
Observational (n=1,400)
Does Doppler echocardiography accurately estimate systolic pulmonary artery pressure compared to right heart catheterization in patients with severe aortic stenosis?
Doppler echocardiography provides a reliable and accurate noninvasive estimation of systolic pulmonary artery pressure compared to invasive right heart catheterization in patients with severe aortic stenosis.
Effect estimate: r = 0.820
Absolute Event Rate: 44.7% vs 45.3%
p-value: p=<.0001
OBJECTIVES: The aim of this study was to investigate reliability and accuracy of noninvasive measurement method by echocardiography compared to invasive measurement of systolic pulmonary artery pressure (SPAP) in a large cohort of aortic stenosis (AS) patients. BACKGROUND: Pulmonary hypertension (PH) is common in patients with cardiac disease, especially in left heart disease like severe AS. Invasive measurement by right heart catheterization (RHC) is the gold standard to assess pulmonary pressures. Nevertheless, echocardiography is widely used in everyday practice for estimation of pulmonary pressures and diagnosing PH. METHODS: A total of 1400 patients with AS and full invasive hemodynamic assessment by RHC and noninvasive measurements by Doppler echocardiography were included. RESULTS: Mean patient age was 81.5 ± 6.8 years, and 46.3% were males. SPAP was 44.7 ± 15.1 mm Hg by echocardiography and 45.3 ± 15.2 mm Hg by RHC. Pearson's correlation coefficient was r = .820 (P 40 mm Hg (82.2% sensitivity, 80.2% specificity, 83.1% positive predictive value, 79.2% negative predictive value). CONCLUSIONS: In a large cohort of patients with severe aortic stenosis, we could demonstrate a very good correlation of SPAP between Doppler echocardiography and invasive RHC measurement. Pulmonary hypertension could be diagnosed by echocardiography with high sensitivity and specificity.
Schewel et al. (Wed,) conducted a observational in Severe aortic stenosis (n=1,400). Doppler echocardiography vs. Right heart catheterization (RHC) was evaluated on Systolic pulmonary artery pressure (SPAP) (r = 0.820, p=<.0001). Doppler echocardiography measurement of systolic pulmonary artery pressure correlated strongly with invasive right heart catheterization in patients with severe aortic stenosis (r=0.820, P<0.0001).