The Cause of Hypercalcuria in Sarcoid and Its Treatment With Cortisone and Sodium Phytate 12

Sarcoid is a chronic granulomatous disease of unknown etiology which may involve any or all organ systems (1). Harrell and Fisher (2) in 1939 first called attention to an elevated serum calcium in 6 of 11 patients with sarcoid. Other abnormalities noted were hyperproteinemia, due to hyperglobulinemia, and elevated serum alkaline phosphatase. The blood inorganic phosphorus was not decreased, a major point in the differential diagnosis with hyperparathyroidism. The uri- nary calcium excretion was not reported but we now know that hypercalcuria is common in sar- coid 3 and often the cause of renal stones which are usually composed of calcium oxalate.