Pre-PCI automated function imaging strain values of -4.5% for the LAD territory predicted post-PCI left ventricular function recovery with 84% sensitivity and 75% specificity.
Cohort (n=50)
Does AFI-based strain imaging predict post-PCI LV function recovery in patients with anterior wall myocardial infarction and impaired LVEF?
Pre-PCI two-dimensional strain imaging using automated function imaging provides added value to dobutamine stress echocardiography in predicting LV function recovery after revascularization.
Effect estimate: OR 0.7026 (95% CI 0.54-0.93)
BACKGROUND: Speckle tracking is integrated into echocardiographic systems for evaluation of left ventricular (LV) function by means of automated function imaging (AFI). This study aimed at evaluating role of AFI-based strain in predicting postpercutaneous coronary intervention (PCI) LV function recovery. METHODS: Fifty patients with anterior wall myocardial infarction and impaired LV ejection fraction (LVEF) were prospectively enrolled. All patients showed positive viability results concerning left anterior descending (LAD) artery territory using low-dose dobutamine stress echocardiography (LDSE). All patients underwent strain imaging using AFI (before and after PCI). RESULT: Mean age of the study population was 56.2 ± 5.4 years, 34 (68%) being males. 24 (48%) patients showed post-PCI LV function recovery after 4 months. They showed higher pre-PCI LVEF and AFI-based strain values. Logistic regression analysis presented baseline LVEF as an independent predictor of LV function recovery (Odds ratio = 0.7026, 95% CI: 0.54-0.93). A pre-PCI AFI strain value of -4.5% (sensitivity: 84% and specificity: 75%) for LAD territory and -9.5% (sensitivity and specificity of 50%) for global LV predicted LV function recovery. CONCLUSION: Assessment of global and territorial LV strains using AFI; is of added value upon viability assessment using LDSE. Higher baseline LVEF and strain values are associated with post-PCI LV function recovery.
Mohamed Shehata (Mon,) conducted a cohort in Anterior wall myocardial infarction with impaired LV ejection fraction (n=50). Automated function imaging (AFI) based strain was evaluated on Post-PCI LV function recovery (OR 0.7026, 95% CI 0.54-0.93). Pre-PCI automated function imaging strain values of -4.5% for the LAD territory predicted post-PCI left ventricular function recovery with 84% sensitivity and 75% specificity.
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