irst responders (FRs), including Law enforcement officers (LEOs), firefighters, and paramedics, face repeated trauma exposure and organizational stressors that elevate the risk for post-traumatic stress disorder (PTSD) and common mental disorders (CMDs). Given this disproportionate burden, male FRs, constituting the majority of this workforce, encounter additional help-seeking barriers rooted in occupational culture and masculine role expectations. This narrative review synthesizes evidence (2019–2025) on epidemiology, risk factors, diagnostic strategies, prevention frameworks, treatment modalities, and quality-of-life outcomes associated with PTSD and CMDs among male FRs. A comprehensive literature search was conducted across PubMed, PsycINFO, MEDLINE, and Scopus for peer-reviewed articles published between January 2019 and March 2025 addressing mental health outcomes in first responder populations. PTSD prevalence among FRs ranges from 7–37%, with depression (15–25%), anxiety (15–20%), and hazardous alcohol use (25–30%) frequently co-occurring. Risk determinants include cumulative trauma exposure, moral injury, organizational stressors, shift work-induced sleep disruption, and stigma. Validated screening instruments, including the Posttraumatic Stress Disorder Checklist for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (PCL-5), Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder-7 (GAD-7), demonstrate acceptable psychometric properties in this population. Cognitive processing therapy (CPT), prolonged exposure, and Eye Movement Desensitization and Reprocessing (EMDR) show large effect sizes (Cohen’s d = 0.8–1.5) for PTSD reduction. Integrated management combining psychotherapy with sleep interventions and workplace accommodations yields superior functional outcomes. Male FRs require integrated workplace-based clinical programs addressing trauma exposure, organizational stressors, and cultural barriers. Future research should prioritize longitudinal designs and implementation science approaches.
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