What question did this study set out to answer?

This research aims to improve the production processes for lanthanum radioisotopes 133La and 135La.

June 3, 2026Open Access

Cross-section measurements of lanthanum radioisotopes towards an optimized production of 133La and 135La for theranostic applications

Key Points

This research aims to improve the production processes for lanthanum radioisotopes 133La and 135La.
Measured cross sections of La-133 and La-135 by irradiating BaCO3.
Utilized an 18 MeV medical cyclotron and a beam transfer line.
Optimized irradiation parameters via production yield and purity analysis.
Successfully measured cross sections leading to optimized production conditions.
Achieved higher production yields with improved purity for La-133 and La-135.
Demonstrated effective use of a custom target station for production tests.

Abstract

• Study of the production of La-133 and La-135 with a medical cyclotron. • Measurement of La radioisotope cross sections by irradiating BaCO 3 . • Measurement performed using an 18 MeV medical cyclotron and a beam transfer line. • Nuclear contributions derived using a method based on linear systems of equations. • Study of production yield and purity to optimize irradiation parameters. • Production tests performed using a custom target station.

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Dellepiane et al. (Mon,) studied this question.

synapsesocial.com/papers/6a1fc56bdee9eb8c0dce6e7a https://doi.org/https://doi.org/10.1016/j.apradiso.2026.112727

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