Is the Current Management of Severe Sepsis and Septic Shock Really Evidence Based?

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis2006 · 41 citations
2. 2Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!2000 · 133 citations
3. 3A Controlled Clinical Trial of High-Dose Methylprednisolone in the Treatment of Severe Sepsis and Septic Shock1987 · 1,450 citations
4. 4The Influence of Inadequate Antimicrobial Treatment of Bloodstream Infections on Patient Outcomes in the ICU Setting2000 · 1,799 citations
5. 5A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care1999 · 2,045 citations