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Abstract The time and potential dependence of the conductance process (es) underlying the longlasting afterhyperpolarization (AHP) in the cat's a‐motoneurones were studied. The conductance changes were determined by injection of short current pulses. The conductance time course was characterized by a longlasting exponential decay interrupted by a plateau corresponding to the slower hypcrpolarizing phase of the AHP. By displacing the membrane potential in the subthreshold region with the injection of longlasting current pulses it was found that the conductance was largely unaffected by membrane potential displacements. Similar characteristics were found when calculating the AHP conductance time course from the AHP voltage. It was concluded that the AHP in motoneurones is given by a potassium conductance process with this complex S‐shaped time course. A mathematical expression describing this time course is given.
Baldissera et al. (Thu,) studied this question.
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